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clotiazepam

Small moleculeexperimental

Clotiazepam is a thienodiazepine drug which is a benzodiazepine analog. The clotiazepam molecule differs from benzodiazepines in that the benzene ring has been replaced by a thiophene ring. It possesses anxiolytic, skeletal muscle relaxant, anticonvulsant, sedative properties. Stage 2 NREM sleep is significantly increased by clotiazepam. — Wikipedia

Clinical trial activity

1 trials · 1 clinical orgs · 0 marketing orgs

Phase 1
1
Phase 2
0
Phase 3
0
Phase 4
0

Earliest trial started Mar 11, 2020 (NCT04440423)

Timeline

2020s

  1. Jan 1, 2020

    Earliest Phase 1 Sponsor(trial)

Indications

Studied for

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

CCc1cc2c(s1)N(C)C(=O)CN=C2c1ccccc1Cl
Mol. weight
318.83 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • 2h-thieno(2,3-e)-1,4-diazepin-2-one, 5-(2-chlorophenyl)-7-ethyl-1,3-dihydro-1-methyl-
  • clotiazepam
  • clotiazepam
  • clotiazepam
  • clotiazepam
  • clotiazepam
  • clotiazepam
  • clotiazepam
  • clotiazepamum
  • clotiazepamum
  • clozan
  • clozan
  • rize
  • rize
  • y6047
  • y 6047
  • y-6047

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT04440423Phase 1Mar 11, 2020Grunenthal
Showing 1 of 1 trials
Page 1 / 1

Organizations

Research & Development (1)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
GrunenthalFor profit1112020
1 organizations
Page 1 / 1