allitinib
Small moleculeexperimental
Clinical trial activity
0 trials · 0 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0
Mechanism of action
EGFR inhibitor
Irreversible inhibitor, also potent at ERBB4.
ERBB2 inhibitor
Irreversible inhibitor, also potent at ERBB4.
Chemistry & pharmacology
Loading structure…
SMILES
C=CC(=O)Nc1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1- Mol. weight
- 448.89 g/mol
- Lipinski Ro5
- 1 violation(s)
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL3545244 ↗
- ChEMBLCHEMBL1947204 ↗
Also known as
- all-3
- all-3
- allitinib
- allitinib
- allitinib
- ast1306
- ast 1306
- ast-1306
- ast-1306
- ast-1306