lypressin
Trade name: diapid
Small moleculeapproved
Lypressin is synthetic analog of porcine antidiuretic hormone vasopressin. Itis a cyclic nonapeptide that differs from Arg-vasopressin by one amino acid, containing Lys at residue 8 instead of Arg. Lypressin-containing nasal spray was used to treat diabetes insipidus, but its marketing by Sandoz (Novartis) was discontinued. — NCATS
Clinical trial activity
0 trials · 0 clinical orgs · 2 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0
Timeline
Indications
Approved for
Mechanism of action
Approval history
- approved—
Chemistry & pharmacology
Loading structure…
SMILES
NCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)NCC(N)=O- Mol. weight
- 1056.24 g/mol
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Delivery
- Topical
- Availability
- Discontinued
Oral
No
Parenteral
No
Topical
Yes
Sources
- WikipediaVasopressin ↗
- NCATS7CZF3L922Y ↗
- ChEMBLCHEMBL1200690 ↗
Also known as
- diapid
- diapid
- diapid
- l-8
- l-8
- lypressin
- lypressin
- lypressin
- lypressin
- lypressin
- lypressin
- lypressin
- lypressin
- lypressin
- lysine pitressin
- lysine vasopressin
- lysipressin
- lysopressin
- lysylvasopressin
- syntopressin