← Mechanisms of action
AVPR2
SINGLE PROTEINHomo sapiens
Preferred name: Vasopressin V2 receptor ChEMBL ↗
Linked proteins
Drugs acting on this target (14)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| fedovapagon | Agonist | experimental | Small molecule | AVPR2 agonist |
| vasopressin (vasostrict) | Agonist | approved | Animal product | AVPR2 agonist |
| velmupressin | Agonist | experimental | Small molecule | AVPR2 agonist |
| bay 1753011 | Antagonist | experimental | Small molecule | AVPR2 antagonist |
| conivaptan (vaprisol) | Antagonist | approved | Small molecule | AVPR2 antagonist |
| lixivaptan | Antagonist | experimental | Small molecule | AVPR2 antagonist |
| opc 131461 | Antagonist | experimental | Small molecule | AVPR2 antagonist |
| opc-41601 | Antagonist | experimental | Small molecule | AVPR2 antagonist |
| opc-61815 | Antagonist | experimental | Small molecule | AVPR2 antagonist |
| physulime | Antagonist | experimental | Small molecule | Vasopressin V2 receptor antagonist |
| satavaptan | Antagonist | experimental | Small molecule | AVPR2 antagonist |
| tolvaptan (samsca) | Antagonist | approved | Small molecule | AVPR2 antagonist |
| terlipressin (Terlivaz) | Binding agent | approved | Peptide | Vasopressin V2 receptor binding agent |
| ro5028442 | Inhibitor | experimental | Small molecule | AVPR2 inhibitor |