CDEK
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gpc3 car-t cell

Cell therapyexperimental

Clinical trial activity

39 trials · 28 clinical orgs · 0 marketing orgs

Phase 1
34
Phase 2
12
Phase 3
0
Phase 4
0

Earliest trial started Mar 1, 2015 (NCT02395250)

Timeline

2010s

  1. Jan 1, 2015

    Earliest Phase 1 Sponsor(trial)

Indications

Studied for

Mechanism of action

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Also known as

  • anti-gpc3 car t
  • car-gpc3 t cells
  • gpc3 car-t cell
  • gpc3-cart cells
  • retroviral vector-transduced autologous t cells to express anti-gpc3 cars
  • tai-gpc3-cart cells

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07224568Phase 1Apr 1, 2026University of Washington
NCT06198296Phase 1Jan 1, 2026Baylor University
NCT07148050Phase 1Dec 15, 2025University of Washington
NCT06815432Phase 1Dec 3, 2025Baylor University
NCT06968195Phase 1Nov 30, 2025State University of New York, Buffalo
NCT06900764N/AOct 10, 2025Huazhong University of Science and Technology
NCT07040917Early Phase 1 (Phase 1)Sep 30, 2025People's Liberation Army of China
NCT07067255Phase 1/Phase 2 (Phase 2)Apr 29, 2025Essen Biotech
NCT06768905Phase 1/Phase 2 (Phase 2)Apr 25, 2025Actinium Pharmaceuticals, The University of Texas, Dallas
NCT06762119Early Phase 1 (Phase 1)Jan 10, 2025Zhejiang University
NCT06641453Phase 1/Phase 2 (Phase 2)Nov 15, 2024People's Liberation Army of China, UTC Therapeutics Inc.
NCT06461624Phase 1Jul 1, 2024People's Liberation Army of China, Zhejiang University
NCT06724835Phase 1Mar 11, 2024Government of China
NCT07097207Phase 1/Phase 2 (Phase 2)Oct 1, 2023Shenzhen University
NCT04715191Phase 1Jul 31, 2023Baylor University
NCT05926726N/AJan 1, 2023Jiao Tong University
NCT05620706N/ANov 1, 2022Shenzhen University
NCT05344664Phase 1Apr 14, 2022Peking University
NCT06144385Phase 1Mar 24, 2022Huazhong University of Science and Technology, Shanghai Ming Ju Biotechnology Co., Ltd.
NCT05120271Phase 1/Phase 2 (Phase 2)Jan 31, 2022Accord Research
Showing 20 of 39 trials
Page 1 / 2

Organizations

Research & Development (28)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
People's Liberation Army of ChinaGovernment7322017
Jiao Tong UniversityAcademic/Hospital6332015
CARsgen Therapeutics, Ltd.For profit5222016
Baylor UniversityAcademic/Hospital4412021
Zhejiang UniversityAcademic/Hospital4312019
Huazhong University of Science and TechnologyAcademic/Hospital3222021
Shanghai GeneChem Co., Ltd.For profit3312016
Jinan UniversityAcademic/Hospital2212015
Shenzhen UniversityAcademic/Hospital2222022
The University of Texas, DallasAcademic/Hospital2122021
University of WashingtonAcademic/Hospital2212025
Accord ResearchFor profit1112022
Actinium PharmaceuticalsFor profit1012025
Beijing Immunochina Medical Science & Technology Co., Ltd.For profit1112019
China ImmunotechFor profit1012020
Essen BiotechFor profit1112025
Fudan UniversityAcademic/Hospital1012016
Government of ChinaGovernment1112024
Nanjing UniversityAcademic/Hospital1112019
National Cancer Institute (NCI)Government1112021
28 organizations
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