CDEK
← Mechanisms of action

GPC3

SINGLE PROTEINHomo sapiens
Preferred name: Glypican-3 ChEMBL ↗

Linked proteins

Drugs acting on this target (44)

Active Pharmaceutical Ingredient Mechanism Type ▲ Approval Status API Type Mechanism of Action
codrituzumabAdccexperimentalmAbGPC3
sar444200AntagonistexperimentalmAbGPC3
anti-gpc3-irdye800cwBinding agentexperimentalmAbGPC3
CM350Binding agentexperimentalmAbGPC3
ery974Binding agentexperimentalmAbGPC3 binding agent
armored and gpc3-targeted autologous car t-cellImmunity, passiveexperimentalCell therapyGPC3 immunity, passive
azd5851Immunity, passiveexperimentalCell therapyimmunity, passive - GPC3
c-car031Immunity, passiveexperimentalCell therapyGPC3 immunity, passive
ct0180 cellsImmunity, passiveexperimentalCell therapyimmunity, passive - GPC3
ct0181 cellsImmunity, passiveexperimentalCell therapyimmunity, passive - GPC3
ect204 t cellsImmunity, passiveexperimentalCell therapyimmunity, passive - GPC3
eu307 car-t cellImmunity, passiveexperimentalCell therapyimmunity, passive - GPC3
gap t cellsImmunity, passiveexperimentalCell therapyimmunity, passive - GPC3
gc511b car-t cellImmunity, passiveexperimentalCell therapyGPC3 immunity, passive
gkl-006Immunity, passiveexperimentalCell therapyGPC3 immunity, passive
glycar t cellsImmunity, passiveexperimentalCell therapyimmunity, passive - GPC3
gpc2 car t cellsImmunity, passiveexperimentalCell therapyGPC3 immunity, passive
gpc3 and/or tgfβ targeting car-t cellsImmunity, passiveexperimentalCell therapyimmunity, passive - gpc3
gpc3 car-t cellImmunity, passiveexperimentalCell therapyimmunity, passive - GPC3
mt-303Immunity, passiveexperimentalCell therapyGPC3 immunity, passive
ori-c101Immunity, passiveexperimentalCell therapyimmunity, passive - GPC3
oric902Immunity, passiveexperimentalCell therapyGPC3 immunity, passive
sn301aImmunity, passiveexperimentalCell therapyGPC3 immunity, passive
tak-102Immunity, passiveexperimentalCell therapyimmunity, passive - GPC3
tc-car031Immunity, passiveexperimentalCell therapyimmunity, passive - GPC3
tils and car-tils targeting her2, mesothelin, psca, muc1, lewis-y, gpc3, axl, egfr, claudin18.2/6, ror1, gd1, or b7-h3Immunity, passiveexperimentalCell therapyimmunity, passive - gpc3
68ga-agpc3InhibitorexperimentalmAbGPC3 inhibitor
azd9793InhibitorexperimentalmAbGPC3 inhibitor
bay 3547926InhibitorexperimentalmAbGPC3 inhibitor
bc2027InhibitorexperimentalmAbGPC3 inhibitor
bgb-b2033InhibitorexperimentalmAbGPC3 inhibitor
bms-986183InhibitorexperimentalmAbGPC3 inhibitor
cg-102-12cInhibitorexperimentalSmall moleculeGPC3 inhibitor
codrituzumabInhibitorexperimentalmAbGlypican-3 inhibitor
gc33InhibitorexperimentalmAbGPC3 inhibitor
ivb103InhibitorexperimentalRecombinant proteinGPC3 inhibitor
jmt106InhibitorexperimentalRecombinant proteinGPC3 inhibitor
mrg006aInhibitorexperimentalmAbGPC3 inhibitor
NWRD06InhibitorexperimentalGene therapyinhibitor - GPC3
ro5137382InhibitorexperimentalmAbGPC3 inhibitor
zw251InhibitorexperimentalmAbGPC3 inhibitor
131i-agpc3RadiodepletionexperimentalmAbGPC3 radiodepletion
ryz801RadiodepletionexperimentalPeptideGPC3 radiodepletion
68ga-xh06RadiopharmaceuticalexperimentalSmall moleculeGPC3 radiopharmaceutical