← Mechanisms of action
GAA
SINGLE PROTEINHomo sapiens
Preferred name: Lysosomal alpha-glucosidase ChEMBL ↗
Linked proteins
Drugs acting on this target (8)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| miglitol (glyset) | Inhibitor | approved | Small molecule | GAA inhibitor |
| duvoglustat | Stabiliser | experimental | Small molecule | GAA stabiliser |
| ab-1009 | Supplementation | experimental | Gene therapy | GAA supplementation |
| alglucosidase alfa (myozyme) | Supplementation | approved | Recombinant protein | GAA supplementation |
| crg003 | Supplementation | experimental | Gene therapy | GAA supplementation |
| dnl952 | Supplementation | experimental | Recombinant protein | GAA supplementation |
| gc301 | Supplementation | experimental | Gene therapy | GAA supplementation |
| Reveglucosidase alfa | Supplementation | experimental | Recombinant protein | GAA supplementation |