← Mechanisms of action

Hypoxia inducible factors; HIF-1-alpha, HIF-2-alpha

PROTEIN FAMILYHomo sapiens

Linked proteins

Drugs acting on this target (3)

Active Pharmaceutical Ingredient Mechanism Type Approval Status API Type Mechanism of Action
Belzutifan (Welireg)AntagonistapprovedSmall moleculeHypoxia inducible factors; HIF-1-alpha, HIF-2-alpha antagonist
dff332InhibitorexperimentalSmall moleculeHypoxia inducible factors; HIF-1-alpha, HIF-2-alpha inhibitor
molidustatInhibitorexperimentalSmall moleculeHypoxia inducible factors; HIF-1-alpha, HIF-2-alpha inhibitor