← Mechanisms of action
PLK1
SINGLE PROTEINHomo sapiens
Preferred name: Serine/threonine-protein kinase PLK1 ChEMBL ↗
Linked proteins
Drugs acting on this target (12)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| tkm-080301 | Antisense inhibitor | experimental | Nucleic acid | PLK1 antisense inhibitor |
| bi-2536 | Inhibitor | experimental | Small molecule | PLK1 inhibitor |
| cafusertib | Inhibitor | experimental | Small molecule | PLK1 inhibitor |
| cafusertib | Inhibitor | experimental | Small molecule | PLK1 inhibitor |
| cyc140 | Inhibitor | experimental | Small molecule | PLK1 inhibitor |
| gsk 461364 | Inhibitor | experimental | Small molecule | PLK1 inhibitor |
| ivx-214 | Inhibitor | experimental | Small molecule | PLK1 inhibitor |
| mk-1496 | Inhibitor | experimental | Small molecule | PLK1 inhibitor |
| nms-1286937 | Inhibitor | experimental | Small molecule | PLK1 inhibitor |
| onvansertib | Inhibitor | experimental | Small molecule | PLK1 inhibitor |
| tak-960 | Inhibitor | experimental | Small molecule | PLK1 inhibitor |
| volasertib | Inhibitor | experimental | Small molecule | PLK1 inhibitor |