← Mechanisms of action
ITGA4
SINGLE PROTEINHomo sapiens
Preferred name: Integrin alpha-4 ChEMBL ↗
Linked proteins
Drugs acting on this target (9)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| axr-159 | Antagonist | experimental | Small molecule | ITGA4 antagonist |
| gs-1427 | Antagonist | experimental | Small molecule | ITGA4 antagonist |
| ro0506997 | Antagonist | experimental | Small molecule | ITGA4 antagonist |
| atl1102 | Antisense inhibitor | experimental | Nucleic acid | ITGA4 antisense inhibitor |
| biib107 | Inhibitor | experimental | mAb | ITGA4 inhibitor |
| natalizumab (tysabri) | Inhibitor | approved | mAb | ITGA4 inhibitor |
| spy001 | Inhibitor | experimental | mAb | ITGA4 inhibitor |
| trk-170 | Inhibitor | experimental | Small molecule | ITGA4 inhibitor |
| Zaurategrast | Inhibitor | experimental | Small molecule | ITGA4 inhibitor |