← Mechanisms of action
Glutamate receptor ionotropic AMPA
PROTEIN COMPLEX GROUPHomo sapiens
Linked proteins
Drugs acting on this target (11)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| irampanel | Antagonist | experimental | Small molecule | Glutamate receptor ionotropic AMPA antagonist |
| perampanel (fycompa) | Antagonist | approved | Small molecule | Glutamate receptor ionotropic AMPA antagonist |
| selurampanel | Antagonist | experimental | Small molecule | Glutamate receptor ionotropic AMPA antagonist |
| tezampanel | Antagonist | experimental | Small molecule | Glutamate receptor ionotropic AMPA antagonist |
| topiramate (topamax) | Antagonist | approved | Small molecule | Glutamate receptor ionotropic AMPA antagonist |
| zonampanel monohydrate | Antagonist | experimental | Small molecule | Glutamate receptor ionotropic AMPA antagonist |
| cx-1739 | Positive allosteric modulator | experimental | Small molecule | Glutamate receptor ionotropic AMPA positive allosteric modulator |
| farampator | Positive allosteric modulator | experimental | Small molecule | Glutamate receptor ionotropic AMPA positive allosteric modulator |
| mibampator | Positive allosteric modulator | experimental | Small molecule | Glutamate receptor ionotropic AMPA positive allosteric modulator |
| org-26576 | Positive allosteric modulator | experimental | Small molecule | Glutamate receptor ionotropic AMPA positive allosteric modulator |
| pf-04958242 | Positive allosteric modulator | experimental | Small molecule | Glutamate receptor ionotropic AMPA positive allosteric modulator |