← Mechanisms of action
C1S
SINGLE PROTEINHomo sapiens
Preferred name: Complement C1s ChEMBL ↗
Linked proteins
Drugs acting on this target (12)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| gt005 | Activator | experimental | Gene therapy | C1S activator |
| sutimlimab (Enjaymo) | Antagonist | approved | mAb | C1S antagonist |
| bivv020 | Inhibitor | experimental | mAb | C1S inhibitor |
| C1 Esterase Inhibitor (Human) (Cinryze) | Inhibitor | approved | Recombinant protein | Complement C1s inhibitor |
| csl830 | Inhibitor | experimental | Biological | C1S inhibitor |
| dnth103 | Inhibitor | experimental | mAb | C1S inhibitor |
| ray121 | Inhibitor | experimental | mAb | C1S inhibitor |
| rls-0071 | Inhibitor | experimental | Peptide | C1S inhibitor |
| sar446597 | Inhibitor | experimental | Gene therapy | C1S inhibitor |
| shp623 | Inhibitor | experimental | Recombinant protein | C1S inhibitor |
| sutimlimab (Enjaymo) | Inhibitor | approved | mAb | Complement C1s inhibitor |
| tnt009 | Inhibitor | experimental | mAb | C1S inhibitor |