← Mechanisms of action
CDK6
SINGLE PROTEINHomo sapiens
Preferred name: Cyclin-dependent kinase 6 ChEMBL ↗
Linked proteins
Drugs acting on this target (33)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| btx-9341 | Degrader | experimental | Small molecule | CDK6 degrader |
| 7-hydroxystaurosporine | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| abemaciclib (verzenio) | Inhibitor | approved | Small molecule | CDK6 inhibitor |
| alvocidib | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| bpi-1178 | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| bpi-16350 | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| cs3002 | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| dalpiciclib | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| darcilide | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| elv001 | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| eth-155008 | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| fcn-437c | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| g1t28-1 | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| g1t38 | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| gdc-4198 | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| glr2007 | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| hs-10342 | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| Lerociclib | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| nuv-422 | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| pf-06842874 | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| pf-06873600 | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| prt3645 | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| qls12004 | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| rgt-419b | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| ribociclib (kisqali) | Inhibitor | approved | Small molecule | CDK6 inhibitor |
| sph6516 | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| syh2043 | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| tqb3303 | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| trilaciclib (Cosela) | Inhibitor | approved | Small molecule | Cyclin-dependent kinase 6 inhibitor |
| ty-302 | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| tyk-00540 | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| uct-03-008 | Inhibitor | experimental | Small molecule | CDK6 inhibitor |
| xh-30002 | Inhibitor | experimental | Small molecule | CDK6 inhibitor |