CDEK
← Mechanisms of action

CXCR4

SINGLE PROTEINHomo sapiens
Preferred name: C-X-C chemokine receptor type 4 ChEMBL ↗

Linked proteins

Drugs acting on this target (31)

Active Pharmaceutical Ingredient Mechanism Type ▲ Approval Status API Type Mechanism of Action
balixafortideAntagonistexperimentalPeptideCXCR4 antagonist
bkt-140AntagonistexperimentalPeptideCXCR4 antagonist
burixaforAntagonistexperimentalSmall moleculeCXCR4 antagonist
ctce-9908AntagonistexperimentalSmall moleculeCXCR4 antagonist
dociparstatAntagonistexperimentalSmall moleculeCXCR4 antagonist
leo 35299AntagonistexperimentalSmall moleculeCXCR4 antagonist
Mavorixafor (Xolremdi)AntagonistapprovedSmall moleculeC-X-C chemokine receptor type 4 antagonist
mb1707AntagonistexperimentalSmall moleculeCXCR4 antagonist
Motixafortide (Aphexda)AntagonistapprovedPeptideC-X-C chemokine receptor type 4 antagonist
msx-122AntagonistexperimentalSmall moleculeCXCR4 antagonist
sctv04cAntagonistexperimentalSmall moleculeCXCR4 antagonist
ga-68-cxcr4Binding agentexperimentalRecombinant proteinCXCR4 binding agent
cxcr4 ccr9 car-tImmunity, passiveexperimentalCell therapyCXCR4 immunity, passive
[177lu]lu-pentixatherInhibitorexperimentalPeptideCXCR4 inhibitor
ad-214InhibitorexperimentalmAbCXCR4 inhibitor
alx-0651InhibitorexperimentalmAbCXCR4 inhibitor
balixafortideInhibitorexperimentalPeptideCXCR4 inhibitor
bkt-140InhibitorexperimentalPeptideCXCR4 inhibitor
bl-8040InhibitorexperimentalPeptideCXCR4 inhibitor
burixaforInhibitorexperimentalSmall moleculeCXCR4 inhibitor
csl412InhibitorexperimentalVaccineCXCR4 inhibitor
gmi-1359InhibitorexperimentalSmall moleculeCXCR4 inhibitor
gpc-100InhibitorexperimentalSmall moleculeCXCR4 inhibitor
ly2510924InhibitorexperimentalPeptideCXCR4 inhibitor
ly2624587InhibitorexperimentalmAbCXCR4 inhibitor
pentixaforInhibitorexperimentalPeptideCXCR4 inhibitor
pf-06747143InhibitorexperimentalmAbCXCR4 inhibitor
ulocuplumabInhibitorexperimentalmAbCXCR4 inhibitor
usl311InhibitorexperimentalSmall moleculeCXCR4 inhibitor
plerixafor (mozobil)Partial agonistapprovedSmall moleculeCXCR4 partial agonist
68ga-jh12RadiopharmaceuticalexperimentalSmall moleculeCXCR4 radiopharmaceutical