balixafortide
Peptideexperimental
Clinical trial activity
8 trials · 9 clinical orgs · 0 marketing orgs
Phase 1
5
Phase 2
5
Phase 3
1
Phase 4
0
Earliest trial started Apr 1, 2009 (NCT01105403)
Timeline
Indications
Studied for
- Breast Neoplasms · Phase 3
- Healthy Volunteers · Phase 1
- Leukemia, Lymphocytic, Chronic, B-Cell · Phase 1/Phase 2
- Leukemia, Myeloid, Acute · Phase 1/Phase 2
- Leukemia, Myeloid, Chronic-Phase · Phase 1/Phase 2
- Lymphoma, Non-Hodgkin · Phase 1/Phase 2
- Multiple Myeloma · Phase 2
- Myelodysplastic Syndromes · Phase 1/Phase 2
- Myeloproliferative Disorders · Phase 1/Phase 2
- Myocardial Infarction · Phase 2
- Pancreatic Neoplasms · Phase 1
- Precursor B-Cell Lymphoblastic Leukemia-Lymphoma · Phase 1/Phase 2
Mechanism of action
- C-X-C chemokine receptor type 4ANTAGONIST
CXCR4 antagonist
- C-X-C chemokine receptor type 4INHIBITOR
CXCR4 inhibitor
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL3545105 ↗
Also known as
- pol6326
- pol6326
- pol-6326
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06981806 | Phase 1 | Jan 31, 2026 | Cedars-Sinai Medical Center |
| NCT04826016 | Phase 1/Phase 2 (Phase 2) | Jul 31, 2021 | MedSIR, Quiron Group, Barcelona (Spain), University of Vermont |
| NCT03786094 | Phase 3 | Jun 14, 2019 | Polyphor Ltd. |
| NCT01905475 | Phase 2 | Jul 1, 2013 | Gottfried Wilhelm Leibniz Universität Hannover, Polyphor Ltd. |
| NCT01837095 | Phase 1 | Jun 1, 2013 | Polyphor Ltd. |
| NCT01413568 | Phase 1/Phase 2 (Phase 2) | Apr 1, 2012 | Polyphor Ltd., University of Utah |
| NCT01841476 | Phase 1 | Feb 1, 2012 | J. W. Goethe University, Polyphor Ltd. |
| NCT01105403 | Phase 2 | Apr 1, 2009 | Polyphor Ltd., University of Heidelberg |
Showing 8 of 8 trials
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Organizations
Research & Development (9)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Polyphor Ltd. | For profit | 6 | 6 | 3 | 2009 |
| Cedars-Sinai Medical Center | Academic/Hospital | 1 | 1 | 1 | 2026 |
| Gottfried Wilhelm Leibniz Universität Hannover | Academic/Hospital | 1 | 0 | 1 | 2013 |
| J. W. Goethe University | Academic/Hospital | 1 | 0 | 1 | 2012 |
| MedSIR | Academic/Hospital | 1 | 1 | 1 | 2021 |
| Quiron Group, Barcelona (Spain) | Academic/Hospital | 1 | 0 | 1 | 2021 |
| University of Heidelberg | Academic/Hospital | 1 | 0 | 1 | 2009 |
| University of Utah | Academic/Hospital | 1 | 0 | 1 | 2012 |
| University of Vermont | Academic/Hospital | 1 | 0 | 1 | 2021 |
9 organizations
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