← Mechanisms of action
ACVR1
SINGLE PROTEINHomo sapiens
Preferred name: Activin receptor type-1 ChEMBL ↗
Linked proteins
Drugs acting on this target (6)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| bone morphogenetic protein-2 | Agonist | experimental | Recombinant protein | Activin receptor type-1 agonist |
| epoetin (Epogen) | Agonist | approved | Recombinant protein | Activin receptor type-1 agonist |
| blu-782 | Inhibitor | experimental | Small molecule | ACVR1 inhibitor |
| incb000928 | Inhibitor | experimental | Small molecule | ACVR1 inhibitor |
| pacritinib (Vonjo) | Inhibitor | approved | Small molecule | Activin receptor type-1 inhibitor |
| tp-0184 | Inhibitor | experimental | Small molecule | ACVR1 inhibitor |