← Mechanisms of action
XPO1
SINGLE PROTEINHomo sapiens
Preferred name: Exportin-1 ChEMBL ↗
Linked proteins
Drugs acting on this target (10)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| selinexor (Xpovio) | Antagonist | approved | Small molecule | XPO1 antagonist |
| wj01024 | Antagonist | experimental | Small molecule | XPO1 antagonist |
| BIIB100 | Inhibitor | experimental | Small molecule | XPO1 inhibitor |
| Eltanexor | Inhibitor | experimental | Small molecule | XPO1 inhibitor |
| kpt-330 | Inhibitor | experimental | Small molecule | XPO1 inhibitor |
| kpt-8602 | Inhibitor | experimental | Small molecule | XPO1 inhibitor |
| sl-801 | Inhibitor | experimental | Small molecule | XPO1 inhibitor |
| verdinexor | Inhibitor | experimental | Small molecule | XPO1 inhibitor |
| wj01075 | Inhibitor | experimental | Small molecule | XPO1 inhibitor |
| wjb001 | Inhibitor | experimental | Small molecule | XPO1 inhibitor |