← Mechanisms of action
botA
SINGLE PROTEINClostridium botulinum
Preferred name: Botulinum neurotoxin type A ChEMBL ↗
Linked proteins
Drugs acting on this target (15)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| daxibotulinumtoxinA (Daxxify) | Agonist | approved | Recombinant protein | botA agonist |
| prabotulinumtoxinA (Jeuveau) | Agonist | approved | Biological | botA agonist |
| botulism antitoxin heptavalent (a, b, c, d, e, f, g) - (equine) (BAT) | Antagonist | approved | Animal product | botA antagonist |
| botulism antitoxin bivalent (equine) types a and b | Immunity, passive | approved | Biological | botA immunity, passive |
| g03-52-01 | Immunity, passive | experimental | mAb | botA immunity, passive |
| ntm-1633 | Immunity, passive | experimental | mAb | botA immunity, passive |
| b11-fc | Inhibitor | experimental | mAb | botA inhibitor |
| bezlotoxumab (zinplava) | Inhibitor | approved | mAb | botA inhibitor |
| botulism immune globulin (BabyBIG) | Inhibitor | approved | Biological | botA inhibitor |
| ntm-1632 | Inhibitor | experimental | mAb | botA inhibitor |
| ntm-1634 | Inhibitor | experimental | mAb | botA inhibitor |
| xoma 3ab | Inhibitor | experimental | mAb | botA inhibitor |
| eb-001 | Supplementation | experimental | Biological | botA supplementation |
| jtm201 | Supplementation | experimental | Biological | botA supplementation |
| yy001 | Supplementation | experimental | Recombinant protein | botA supplementation |