← Mechanisms of action
AXL
SINGLE PROTEINHomo sapiens
Preferred name: Tyrosine-protein kinase receptor UFO ChEMBL ↗
Linked proteins
Drugs acting on this target (33)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| 3d229 | Antagonist | experimental | Recombinant protein | AXL antagonist |
| cd73/axl.hyposti.car-t cells | Immunity, passive | experimental | Cell therapy | AXL immunity, passive |
| cd73/axl.hyposti.car-t cells | Immunity, passive | experimental | Cell therapy | AXL immunity, passive |
| tils and car-tils targeting her2, mesothelin, psca, muc1, lewis-y, gpc3, axl, egfr, claudin18.2/6, ror1, gd1, or b7-h3 | Immunity, passive | experimental | Cell therapy | AXL immunity, passive |
| ab801 | Inhibitor | experimental | Small molecule | AXL inhibitor |
| acr246 | Inhibitor | experimental | mAb | AXL inhibitor |
| adct-601 | Inhibitor | experimental | mAb | AXL inhibitor |
| BA3011 | Inhibitor | experimental | mAb | AXL inhibitor |
| bemcentinib | Inhibitor | experimental | Small molecule | AXL inhibitor |
| bgb149 | Inhibitor | experimental | mAb | AXL inhibitor |
| bpi-9016 | Inhibitor | experimental | Small molecule | AXL inhibitor |
| ds-1205c | Inhibitor | experimental | Small molecule | AXL inhibitor |
| fc084csa | Inhibitor | experimental | Small molecule | AXL inhibitor |
| gilteritinib | Inhibitor | approved | Small molecule | AXL inhibitor |
| hh30134 | Inhibitor | experimental | Small molecule | AXL inhibitor |
| humax-axl-adc | Inhibitor | experimental | mAb | AXL inhibitor |
| kc1036 | Inhibitor | experimental | Small molecule | AXL inhibitor |
| lp-51 | Inhibitor | experimental | Small molecule | AXL inhibitor |
| ningetinib | Inhibitor | experimental | Small molecule | AXL inhibitor |
| ntq2494 | Inhibitor | experimental | Small molecule | AXL inhibitor |
| ono-7475 | Inhibitor | experimental | Small molecule | AXL inhibitor |
| pf-07265807 | Inhibitor | experimental | Small molecule | AXL inhibitor |
| q702 | Inhibitor | experimental | Small molecule | AXL inhibitor |
| r-428 | Inhibitor | experimental | Small molecule | AXL inhibitor |
| rxdx-106 | Inhibitor | experimental | Small molecule | AXL inhibitor |
| sitravatinib | Inhibitor | experimental | Small molecule | AXL inhibitor |
| ski-g-801 | Inhibitor | experimental | Small molecule | AXL inhibitor |
| slc-391 | Inhibitor | experimental | Small molecule | AXL inhibitor |
| tp-0903 | Inhibitor | experimental | Small molecule | AXL inhibitor |
| tt-00973 | Inhibitor | experimental | Small molecule | AXL inhibitor |
| xl092 | Inhibitor | experimental | Small molecule | AXL inhibitor |
| xw-lth-03 | Inhibitor | experimental | mAb | AXL inhibitor |
| xzb-0004 | Inhibitor | experimental | Small molecule | AXL inhibitor |