← Mechanisms of action
HRH3
SINGLE PROTEINHomo sapiens
Preferred name: Histamine H3 receptor ChEMBL ↗
Linked proteins
Drugs acting on this target (31)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| cipralisant | Agonist | experimental | Small molecule | HRH3 agonist |
| mk-3134 | Agonist | experimental | Small molecule | HRH3 agonist |
| abt-288 | Antagonist | experimental | Small molecule | HRH3 antagonist |
| az12807110 | Antagonist | experimental | Small molecule | HRH3 antagonist |
| azd5213 | Antagonist | experimental | Small molecule | HRH3 antagonist |
| bavisant | Antagonist | experimental | Small molecule | HRH3 antagonist |
| betahistine mesilate | Antagonist | experimental | Small molecule | HRH3 antagonist |
| bp1.3656 | Antagonist | experimental | Small molecule | HRH3 antagonist |
| cbp-174 | Antagonist | experimental | Small molecule | HRH3 antagonist |
| gsk-1004723 | Antagonist | experimental | Small molecule | Histamine H3 receptor antagonist |
| gsk189254 | Antagonist | experimental | Small molecule | HRH3 antagonist |
| gsk239512 | Antagonist | experimental | Small molecule | HRH3 antagonist |
| irdabisant | Antagonist | experimental | Small molecule | HRH3 antagonist |
| jnj-17216498 | Antagonist | experimental | Small molecule | HRH3 antagonist |
| jnj-39220675 | Antagonist | experimental | Small molecule | Histamine H3 receptor antagonist |
| pf-03654746 | Antagonist | experimental | Small molecule | HRH3 antagonist |
| pf-03654764 | Antagonist | experimental | Small molecule | HRH3 antagonist |
| abt-652 | Inhibitor | experimental | Small molecule | HRH3 inhibitor |
| gsk 835726 | Inhibitor | experimental | Small molecule | HRH3 inhibitor |
| gsk-1004723 | Inhibitor | experimental | Small molecule | HRH3 inhibitor |
| hpp404 | Inhibitor | experimental | Small molecule | HRH3 inhibitor |
| jnj-39220675 | Inhibitor | experimental | Small molecule | HRH3 inhibitor |
| lml134 | Inhibitor | experimental | Small molecule | HRH3 inhibitor |
| Samelisant | Inhibitor | experimental | Small molecule | HRH3 inhibitor |
| sar110894 | Inhibitor | experimental | Small molecule | HRH3 inhibitor |
| alto-203 | Inverse agonist | experimental | Small molecule | HRH3 inverse agonist |
| apd916 | Inverse agonist | experimental | Small molecule | HRH3 inverse agonist |
| enerisant | Inverse agonist | experimental | Small molecule | HRH3 inverse agonist |
| mk-0249 | Inverse agonist | experimental | Small molecule | HRH3 inverse agonist |
| pitolisant (Wakix) | Inverse agonist | approved | Small molecule | HRH3 inverse agonist |
| Samelisant | Inverse agonist | experimental | Small molecule | Histamine H3 receptor inverse agonist |