pf-03654746

Small moleculeexperimental

Clinical trial activity

7 trials · 3 clinical orgs · 0 marketing orgs

Phase 1
3
Phase 2
4
Phase 3
0
Phase 4
0

Earliest trial started Dec 1, 2007 (NCT00531752)

Timeline

2000s

  1. Jan 1, 2007

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 2008

    Earliest Phase 1 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

CCNC(=O)[C@H]1C[C@@](F)(c2ccc(CN3CCCC3)c(F)c2)C1
Mol. weight
322.4 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • n-ethyl-3-fluoro-3-(3-fluoro-4-(pyrrolidinylmethyl)phenyl)cyclobutanecarboxamide
  • pf03654746
  • pf 03654746
  • pf-03654746
  • pf-03654746
  • pf-03654746
  • pf-03654746
  • pf-03654746

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT01475383Phase 2Apr 1, 2012Pfizer
NCT01028911Phase 1Dec 1, 2009Pfizer
NCT01006122Phase 2Nov 1, 2009Pfizer
NCT01346163Phase 1Apr 1, 2009Pfizer, University of Pennsylvania
NCT00730990Phase 1May 31, 2008Pfizer, Yale University
NCT00531752Phase 2Dec 1, 2007Pfizer
NCT00562120Phase 2Dec 1, 2007Pfizer
Showing 7 of 7 trials
Page 1 / 1

Organizations

Research & Development (3)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
PfizerFor profit7622007
University of PennsylvaniaAcademic/Hospital1112009
Yale UniversityAcademic/Hospital1012008
3 organizations
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