CDEK
← Mechanisms of action

INSR

SINGLE PROTEINHomo sapiens
Preferred name: Insulin receptor ChEMBL ↗

Linked proteins

Drugs acting on this target (28)

Active Pharmaceutical Ingredient Mechanism Type ▲ Approval Status API Type Mechanism of Action
cb4211ActivatorexperimentalSmall moleculeINSR activator
gzr-33AgonistexperimentalRecombinant proteinINSR agonist
gzr102AgonistexperimentalPeptideINSR agonist
hm12470AgonistexperimentalRecombinant proteinINSR agonist
imcy-0098AgonistexperimentalPeptideINSR agonist
insulin degludec (tresiba)AgonistapprovedRecombinant proteinINSR agonist
insulin detemir (Levemir)AgonistapprovedRecombinant proteinINSR agonist
insulin glargine (toujeo)AgonistapprovedRecombinant proteinINSR agonist
insulin glulisine (Apidra)AgonistapprovedRecombinant proteinINSR agonist
insulin human (humulin)AgonistapprovedRecombinant proteinINSR agonist
insulin icodecAgonistexperimentalRecombinant proteinInsulin receptor agonist
insulin lispro (humalog)AgonistapprovedRecombinant proteinINSR agonist
insulin tregopilAgonistexperimentalRecombinant proteinInsulin receptor agonist
Insulin, bovineAgonistapprovedAnimal productINSR agonist
Insulin, porcineAgonistapprovedAnimal productINSR agonist
insulin, regular, beef-porkAgonistapprovedAnimal productINSR agonist
ly3209590AgonistexperimentalSmall moleculeINSR agonist
mk-1092AgonistexperimentalRecombinant proteinINSR agonist
nn1952AgonistexperimentalRecombinant proteinINSR agonist
protamine insulinAgonistapprovedAnimal productINSR agonist
rc98AgonistexperimentalSmall moleculeINSR agonist
ga-nota-r8b4Binding agentexperimentalBiologicsINSR binding agent
bms754807InhibitorexperimentalSmall moleculeINSR inhibitor
ersodetugInhibitorexperimentalmAbINSR inhibitor
kw-2450InhibitorexperimentalSmall moleculeINSR inhibitor
linsitinibInhibitorexperimentalSmall moleculeINSR inhibitor
xoma 358InhibitorexperimentalmAbINSR inhibitor
mk-5160Partial agonistexperimentalSmall moleculeINSR partial agonist