Insulin, bovine
Animal productapproved
Approved
Sep 25, 1950
Clinical trial activity
13 trials · 14 clinical orgs · 3 marketing orgs
Phase 1
0
Phase 2
7
Phase 3
1
Phase 4
4
Earliest trial started Jul 1, 2008 (NCT00867594)
Timeline
1950s
- Sep 25, 1950
Bristol-Myers Squibb — Earliest FDA Approval
- Sep 25, 1950
Bristol-Myers Squibb — Marketing Organization
- Sep 25, 1950
Bristol-Myers Squibb — NDA Secondary Org
- Sep 25, 1950
Bristol-Myers Squibb — NDA Organization
1980s
- Mar 17, 1980
Novo Nordisk — NDA Secondary Org
- Jun 10, 1987
Eli Lilly — NDA Secondary Org
2000s
- Jan 1, 2008
Earliest Phase 2 Sponsor(trial)
Indications
Approved for
Mechanism of action
- Insulin receptorAGONIST
INSR agonist
Approval history
- approvedSep 25, 1950
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Delivery
- Parenteral
- Availability
- Discontinued
Oral
No
Parenteral
Yes
Topical
No
Sources
- ChEMBLCHEMBL1201541 ↗
- NCATS576O9IZ534 ↗
- ChEMBLCHEMBL1201642 ↗
- ChEMBLCHEMBL1201641 ↗
- ChEMBLCHEMBL1201640 ↗
- ChEMBLCHEMBL1201639 ↗
- ChEMBLCHEMBL2108964 ↗
- ChEMBLCHEMBL1201546 ↗
- ChEMBLCHEMBL1201545 ↗
- ChEMBLCHEMBL1201542 ↗
- ChEMBLCHEMBL1201539 ↗
- ChEMBLCHEMBL1201629 ↗
- ChEMBLCHEMBL1201655 ↗
Also known as
- ins hypurin bov isop
- insulin
- insulin
- insulin
- insulin beef
- insulin (beef)
- insulin (beef)
- insulin bovine
- insulin bovine
- insulin purified beef
- insulin purified beef
- insulin purified beef
- insulin susp isophane beef
- insulin susp isophane beef
- insulin susp isophane purified beef
- insulin susp isophane purified beef
- insulin zinc susp beef
- insulin zinc susp beef
- insulin zinc susp extended beef
- insulin zinc susp extended beef
- insulin zinc susp extended beef
- insulin zinc susp extended purified beef
- insulin zinc susp extended purified beef
- insulin zinc susp extended recombinant human
- insulin zinc susp extended recombinant human
- insulin zinc susp prompt beef
- insulin zinc susp prompt beef
- insulin zinc susp purified beef
- insulin zinc susp purified beef
- lente iletin ii
- lente insulin
- lente insulin
- lente insulin
- ormd 0801
- ormd 0801
- protaphane
- protaphane
- regular iletin ii
- semilente insulin
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05768191 | Phase 4 | Jun 15, 2023 | Juvenile Diabetes Research Foundation, Université NAZI BONI |
| NCT03152890 | Phase 4 | May 15, 2017 | Seoul National University |
| NCT03111433 | Phase 2 | Mar 19, 2017 | Ain Shams University |
| NCT02954601 | Phase 2 | Oct 1, 2016 | Integrium, Oramed Pharmaceutical Inc., Orange County Research Center |
| NCT03141827 | Phase 2/Phase 3 (Phase 3) | Apr 14, 2016 | University of Toronto |
| NCT02496000 | Phase 2 | Jun 1, 2015 | Integrium, Oramed Pharmaceutical Inc., Orange County Research Center |
| NCT02535715 | Phase 2 | Jan 1, 2015 | Oramed Pharmaceutical Inc., The University of Texas, Dallas, University of Texas, San Antonio |
| NCT02094534 | Phase 2 | Mar 1, 2014 | Integrium, Oramed Pharmaceutical Inc. |
| NCT01889667 | Phase 2 | Jun 1, 2013 | Integrium, Oramed Pharmaceutical Inc., Orange County Research Center |
| NCT01649466 | Phase 4 | Aug 1, 2012 | Novartis |
| NCT01269996 | Phase 4 | May 1, 2011 | Chinese University of Hong Kong |
| NCT03179280 | N/A | Mar 1, 2011 | Aristotle University of Thessaloniki |
| NCT00867594 | Phase 2 | Jul 1, 2008 | Hebrew University, Oramed Pharmaceutical Inc. |
Showing 13 of 13 trials
Page 1 / 1
Organizations
Research & Development (14)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Oramed Pharmaceutical Inc. | For profit | 6 | 4 | 1 | 2008 |
| Integrium | For profit | 4 | 0 | 1 | 2013 |
| Orange County Research Center | Academic/Hospital | 3 | 0 | 1 | 2013 |
| Ain Shams University | Academic/Hospital | 1 | 1 | 1 | 2017 |
| Aristotle University of Thessaloniki | Academic/Hospital | 1 | 1 | 1 | 2011 |
| Chinese University of Hong Kong | Academic/Hospital | 1 | 1 | 1 | 2011 |
| Hebrew University | Academic/Hospital | 1 | 1 | 1 | 2008 |
| Juvenile Diabetes Research Foundation | Academic/Hospital | 1 | 0 | 1 | 2023 |
| Novartis | For profit | 1 | 1 | 1 | 2012 |
| Seoul National University | Academic/Hospital | 1 | 1 | 1 | 2017 |
| The University of Texas, Dallas | Academic/Hospital | 1 | 0 | 1 | 2015 |
| Université NAZI BONI | Academic/Hospital | 1 | 1 | 1 | 2023 |
| University of Texas, San Antonio | Academic/Hospital | 1 | 1 | 1 | 2015 |
| University of Toronto | Academic/Hospital | 1 | 1 | 1 | 2016 |
14 organizations
Page 1 / 1
Marketing (5)
| Organization | Org type | Relationship | Date |
|---|---|---|---|
| Bristol-Myers Squibb | For profit | MKTG | Sep 25, 1950 |
| Bristol-Myers Squibb | For profit | NDA2 | Sep 25, 1950 |
| Bristol-Myers Squibb | For profit | NDA | Sep 25, 1950 |
| Eli Lilly | For profit | NDA2 | Jun 10, 1987 |
| Novo Nordisk | For profit | NDA2 | Mar 17, 1980 |