← Mechanisms of action
Hepatitis B virus
ORGANISMHepatitis B virus
Drugs acting on this target (141)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| abi-4334 | Antagonist | experimental | Small molecule | Hepatitis B virus antagonist |
| gsk3965193 | Antagonist | experimental | Small molecule | Hepatitis B virus antagonist |
| Haemophilus influenzae Type b Conjugate and Hepatitis B (Recombinant) (Comvax) | Antagonist | approved | Vaccine | Hepatitis B virus antagonist |
| hh-003 | Antagonist | experimental | mAb | Hepatitis B virus antagonist |
| hh-006 | Antagonist | experimental | mAb | Hepatitis B virus antagonist |
| ab-729 | Antisense inhibitor | experimental | Nucleic acid | Hepatitis B virus antisense inhibitor |
| ahb-137 | Antisense inhibitor | experimental | Nucleic acid | Hepatitis B virus antisense inhibitor |
| ahb-171 | Antisense inhibitor | experimental | Nucleic acid | Hepatitis B virus antisense inhibitor |
| arc-520 | Antisense inhibitor | experimental | Nucleic acid | Hepatitis B virus antisense inhibitor |
| arc-521 | Antisense inhibitor | experimental | Nucleic acid | Hepatitis B virus antisense inhibitor |
| bw-20507 | Antisense inhibitor | experimental | Nucleic acid | Hepatitis B virus antisense inhibitor |
| jnj-73763989 | Antisense inhibitor | experimental | Nucleic acid | Hepatitis B virus antisense inhibitor |
| ro7062931 | Antisense inhibitor | experimental | Nucleic acid | Hepatitis B virus antisense inhibitor |
| aIIV-B (HepliSav B) | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| avx70371 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| avx70481 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| brii-179 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| chadox1-hbv | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| cvi-hbv-001 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| cvi-hbv-002 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| diphtheria-tetanus-whole cell pertussis-inactivated poliovirus-haemophilus influenzae b conjugate-hepatitis b vaccine | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| DTaP, inactivated poliovirus, haemophilus influenzae b conjugate, hepatitis b vaccine (Pediarix) | Immunity, active | approved | Vaccine | Hepatitis B virus immunity, active |
| dv-601 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| fp-02.2 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| gs-2829 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| gs-4774 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| gs-6779 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| gsk-287615 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| gsk2231392a | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| gsk3528869a | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| hb-110 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| hb-as02v | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| hbai20 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| HBV DNA vaccine | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| hbv-001 d1 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| hbv-mpl 208129 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| hepadvax | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| hepatitis b vaccine (recombinant) (Recombivax) | Immunity, active | approved | Vaccine | Hepatitis B virus immunity, active |
| hepatitis-a virus (inactivated) / hepatitis-b surface antigen (twinrix) | Immunity, active | approved | Vaccine | Hepatitis B virus immunity, active |
| ino-1800 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| ino-9112 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| isa104 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| jnj-64300535 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| mva-hbv | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| pcmvs2.s | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| ppdpsc18 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| pres hbsag | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| ql-007 | Immunity, active | experimental | Small molecule | Hepatitis B virus immunity, active |
| quinvaxem | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| ro7239958 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| tg1050 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| Therapeutic Hepatitis B Adenovirus | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| tritanrix-hepb | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| tvax-008 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| v232 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| vax-id | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| vron-0200-adc6 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| vvx001 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| wgc0201 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| ys-hbv-002 | Immunity, active | experimental | Vaccine | Hepatitis B virus immunity, active |
| exbivirumab | Immunity, passive | experimental | mAb | Hepatitis B virus immunity, passive |
| gc1102 | Immunity, passive | experimental | mAb | Hepatitis B virus immunity, passive |
| hepatitis b immune globulin (human) (BayHep B) | Immunity, passive | approved | Biological | Hepatitis B virus immunity, passive |
| hepatitis c immune globulin | Immunity, passive | experimental | Biological | Hepatitis B virus immunity, passive |
| libivirumab | Immunity, passive | experimental | mAb | Hepatitis B virus immunity, passive |
| liocyx | Immunity, passive | experimental | Cell therapy | Hepatitis B virus immunity, passive |
| liocyx-m, hbv antigen-specific tcr-redirected t cells | Immunity, passive | experimental | Cell therapy | Hepatitis B virus immunity, passive |
| mrna hbv/tcr t-cells | Immunity, passive | experimental | Cell therapy | Hepatitis B virus immunity, passive |
| qy-1-t | Immunity, passive | experimental | Cell therapy | Hepatitis B virus immunity, passive |
| scg101 | Immunity, passive | experimental | Cell therapy | Hepatitis B virus immunity, passive |
| tavec100 | Immunity, passive | experimental | Cell therapy | Hepatitis B virus immunity, passive |
| tuvirumab | Immunity, passive | experimental | mAb | Hepatitis B virus immunity, passive |
| tv-1106 | Immunity, passive | experimental | mAb | Hepatitis B virus immunity, passive |
| vir-3434 | Immunity, passive | experimental | mAb | Hepatitis B virus immunity, passive |
| ab-836 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| abi-h2158 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| abi-h3733 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| al-3778 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| alg-000184 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| alg-010133 | Inhibitor | experimental | Nucleic acid | Hepatitis B virus inhibitor |
| alg-020572 | Inhibitor | experimental | Nucleic acid | Hepatitis B virus inhibitor |
| alg-125755 | Inhibitor | experimental | Nucleic acid | Hepatitis B virus inhibitor |
| apg-1387 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| arb-001467 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| aro-hbv | Inhibitor | experimental | Nucleic acid | Hepatitis B virus inhibitor |
| arylacenamide | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| ati-2173 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| besifovir | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| cb06-036 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| crma-1001 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| dcr-hbvs | Inhibitor | experimental | Nucleic acid | Hepatitis B virus inhibitor |
| dexelvucitabine | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| edp-514 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| edp-721 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| Efesovir | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| entecavir (baraclude) | Inhibitor | approved | Small molecule | Hepatitis B virus inhibitor |
| epi-003 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| fialuridine | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| freethiadine | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| giga-2339 | Inhibitor | experimental | mAb | Hepatitis B virus inhibitor |
| gls4 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| gsk3228836 | Inhibitor | experimental | Nucleic acid | Hepatitis B virus inhibitor |
| gst-hg121 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| gst-hg131 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| gst-hg141 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| hec121120 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| heptcell | Inhibitor | experimental | Peptide | Hepatitis B virus inhibitor |
| hrs-5635 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| hrs5091 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| ht-101 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| ht-102 | Inhibitor | experimental | mAb | Hepatitis B virus inhibitor |
| imc-i109v-101 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| impt-514 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| inarigivir | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| jlp-1901 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| jnj-440 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| jnj-56136379 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| jnj-64457744 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| jnj-64530440 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| lw231 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| NCO-48 fumarate | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| nvr 3-778 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| pradefovir | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| qls31903 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| rbd1016 | Inhibitor | experimental | Nucleic acid | Hepatitis B virus inhibitor |
| rep 2139 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| rep 2165 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| ro6889678 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| ro7020322 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| ro7049389 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| ro7565020 | Inhibitor | experimental | Allergen | Hepatitis B virus inhibitor |
| sa1211 | Inhibitor | experimental | Nucleic acid | Hepatitis B virus inhibitor |
| tune-401 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| tvav-008 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| valtorcitabine | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| vebicorvir | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| vir-2218 | Inhibitor | experimental | Nucleic acid | Hepatitis B virus inhibitor |
| vnrx-9945 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| xt1061 | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| zm-h1505r | Inhibitor | experimental | Small molecule | Hepatitis B virus inhibitor |
| chad155-hii-hbv | Unclear | experimental | Vaccine | Hepatitis B virus unclear |