← Mechanisms of action
MDM2
SINGLE PROTEINHomo sapiens
Preferred name: p53-binding protein Mdm-2 ChEMBL ↗
Linked proteins
Drugs acting on this target (18)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| astx295 | Antagonist | experimental | Small molecule | MDM2 antagonist |
| bi 3820768 | Antagonist | experimental | Small molecule | MDM2 antagonist |
| bi 907828 | Antagonist | experimental | Small molecule | MDM2 antagonist |
| ro6839921 | Antagonist | experimental | Small molecule | MDM2 antagonist |
| sar405838 | Antagonist | experimental | Small molecule | MDM2 antagonist |
| serdemetan | Antagonist | experimental | Small molecule | MDM2 antagonist |
| kt-253 | Degrader | experimental | Small molecule | MDM2 degrader |
| apg115 | Inhibitor | experimental | Small molecule | MDM2 inhibitor |
| atx-295 | Inhibitor | experimental | Small molecule | MDM2 inhibitor |
| cgm097 | Inhibitor | experimental | Small molecule | MDM2 inhibitor |
| cll442 | Inhibitor | experimental | Small molecule | MDM2 inhibitor |
| idasanutlin | Inhibitor | experimental | Small molecule | MDM2 inhibitor |
| milademetan | Inhibitor | experimental | Small molecule | MDM2 inhibitor |
| navtemadlin | Inhibitor | experimental | Small molecule | MDM2 inhibitor |
| ro5045337 | Inhibitor | experimental | Small molecule | MDM2 inhibitor |
| sa53-os | Inhibitor | experimental | Small molecule | MDM2 inhibitor |
| siremadlin | Inhibitor | experimental | Small molecule | MDM2 inhibitor |
| [68ga] mdm2/mdmx peptide | Radiopharmaceutical | experimental | Peptide | MDM2 radiopharmaceutical |