← Mechanisms of action
CALCRL
SINGLE PROTEINHomo sapiens
Preferred name: Calcitonin gene-related peptide type 1 receptor ChEMBL ↗
Linked proteins
Drugs acting on this target (10)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| davalintide | Agonist | experimental | Peptide | CALCRL agonist |
| atogepant (Qulipta) | Antagonist | approved | Small molecule | CALCRL antagonist |
| erenumab (aimovig) | Antagonist | approved | mAb | CALCRL antagonist |
| mk-3207 | Antagonist | experimental | Small molecule | CALCRL antagonist |
| olcegepant | Antagonist | experimental | Small molecule | CALCRL antagonist |
| rimegepant (Nurtec) | Antagonist | approved | Small molecule | CALCRL antagonist |
| telcagepant | Antagonist | experimental | Small molecule | CALCRL antagonist |
| ubrogepant (Ubrelvy) | Antagonist | approved | Small molecule | CALCRL antagonist |
| zavegepant (zavzpret) | Antagonist | approved | Small molecule | Calcitonin gene-related peptide type 1 receptor antagonist |
| erenumab (aimovig) | Inhibitor | approved | mAb | CALCRL inhibitor |