← Mechanisms of action
HMGCR
SINGLE PROTEINHomo sapiens
Preferred name: HMG-CoA reductase ChEMBL ↗
Linked proteins
Drugs acting on this target (9)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| atorvastatin (lipitor) | Inhibitor | approved | Small molecule | HMGCR inhibitor |
| cerivastatin (baycol) | Inhibitor | withdrawn | Small molecule | HMGCR inhibitor |
| fluvastatin (lescol) | Inhibitor | approved | Small molecule | HMGCR inhibitor |
| lovastatin (mevacor) | Inhibitor | approved | Small molecule | HMGCR inhibitor |
| pitavastatin (livalo) | Inhibitor | approved | Small molecule | HMGCR inhibitor |
| pravastatin (pravachol) | Inhibitor | approved | Small molecule | HMGCR inhibitor |
| rosuvastatin (crestor) | Inhibitor | approved | Small molecule | HMGCR inhibitor |
| simvastatin (zocor) | Inhibitor | approved | Small molecule | HMGCR inhibitor |
| syn-010 | Inhibitor | experimental | Small molecule | HMGCR inhibitor |