← Mechanisms of action
KLK1
SINGLE PROTEINHomo sapiens
Preferred name: Kallikrein 1 ChEMBL ↗
Linked proteins
Drugs acting on this target (13)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| ds-2325a | Antagonist | experimental | Small molecule | KLK1 antagonist |
| avoralstat | Inhibitor | experimental | Small molecule | KLK1 inhibitor |
| dm199 | Inhibitor | experimental | Recombinant protein | KLK1 inhibitor |
| ecallantide (Kalbitor) | Inhibitor | approved | Peptide | KLK1 inhibitor |
| isis 721744 | Inhibitor | experimental | Nucleic acid | KLK1 inhibitor |
| kvd824 | Inhibitor | experimental | Small molecule | Kallikrein 1 inhibitor |
| lanadelumab (takhzyro) | Inhibitor | approved | mAb | KLK1 inhibitor |
| mdpk67b | Inhibitor | experimental | Small molecule | Kallikrein 1 inhibitor |
| qrx003 | Inhibitor | experimental | Small molecule | KLK1 inhibitor |
| sebetralstat (Ekterly) | Inhibitor | approved | Small molecule | KLK1 inhibitor |
| star-0215 | Inhibitor | experimental | mAb | Kallikrein 1 inhibitor |
| thr-149 | Inhibitor | experimental | Small molecule | Kallikrein 1 inhibitor |
| dm199 | Supplementation | experimental | Recombinant protein | KLK1 supplementation |