← Mechanisms of action
IL1R1
SINGLE PROTEINHomo sapiens
Preferred name: Interleukin-1 receptor ChEMBL ↗
Linked proteins
Drugs acting on this target (13)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| il-1 | Agonist | experimental | Recombinant protein | IL1R1 agonist |
| 9mw1911 | Antagonist | experimental | mAb | IL1R1 antagonist |
| diacerein | Antagonist | experimental | Small molecule | IL1R1 antagonist |
| forodesine | Antagonist | experimental | Small molecule | IL1R1 antagonist |
| humantakinogene hadenovec | Antagonist | experimental | Gene therapy | IL1R1 antagonist |
| anti-il1rap chimeric antigen receptor t cells | Immunity, passive | experimental | Cell therapy | IL1R1 immunity, passive |
| amg 719 | Inhibitor | experimental | Recombinant protein | IL1R1 inhibitor |
| can04 | Inhibitor | experimental | mAb | IL1R1 inhibitor |
| cdp-484 | Inhibitor | experimental | mAb | IL1R1 inhibitor |
| ebi-005 | Inhibitor | experimental | Small molecule | IL1R1 inhibitor |
| gsk1827771 | Inhibitor | experimental | mAb | IL1R1 inhibitor |
| kpl-387 | Inhibitor | experimental | mAb | IL1R1 inhibitor |
| medi-8968 | Inhibitor | experimental | mAb | IL1R1 inhibitor |