can04
mAbexperimental
Clinical trial activity
8 trials · 7 clinical orgs · 0 marketing orgs
Phase 1
7
Phase 2
6
Phase 3
0
Phase 4
0
Earliest trial started Sep 19, 2017 (NCT03267316)
Timeline
Indications
Studied for
- Biliary Tract Neoplasms · Phase 1/Phase 2
- Carcinoma, Non-Small-Cell Lung · Phase 1/Phase 2
- Carcinoma, Transitional Cell · Phase 1
- Colorectal Neoplasms · Phase 1/Phase 2
- Leukemia, Myeloid, Acute · Phase 1/Phase 2
- Melanoma · Phase 1
- Myelodysplastic Syndromes · Phase 1/Phase 2
- Neoplasms · Phase 1/Phase 2
- Pancreatic Neoplasms · Phase 1/Phase 2
- Squamous Cell Carcinoma of Head and Neck · Phase 1
- Triple Negative Breast Neoplasms · Phase 1/Phase 2
Mechanism of action
- Interleukin-1 receptorINHIBITOR
IL1R1 inhibitor
Chemistry & pharmacology
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07281716 | Phase 1/Phase 2 (Phase 2) | Dec 31, 2025 | Cantargia AB, Coherus Oncology, Inc., Icahn School of Medicine at Mount Sinai |
| NCT07284485 | Phase 2 | Dec 15, 2025 | Cantargia AB, Icahn School of Medicine at Mount Sinai |
| NCT06548230 | Phase 1/Phase 2 (Phase 2) | Jan 1, 2025 | University of Texas at Houston |
| NCT05181462 | Phase 1/Phase 2 (Phase 2) | Jan 11, 2022 | Cantargia AB, Spanish Breast Cancer Research Group, University of Navarra |
| NCT05116891 | Phase 1/Phase 2 (Phase 2) | Sep 22, 2021 | Cantargia AB |
| NCT04990037 | Phase 1 | Jul 31, 2021 | Cantargia AB |
| NCT04452214 | Phase 1 | Sep 24, 2020 | Cantargia AB |
| NCT03267316 | Phase 1/Phase 2 (Phase 2) | Sep 19, 2017 | Cantargia AB, Free University of Brussels |
Showing 8 of 8 trials
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Organizations
Research & Development (7)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Cantargia AB | For profit | 7 | 5 | 2 | 2017 |
| Icahn School of Medicine at Mount Sinai | Academic/Hospital | 2 | 2 | 1 | 2025 |
| Coherus Oncology, Inc. | For profit | 1 | 0 | 1 | 2025 |
| Free University of Brussels | Academic/Hospital | 1 | 0 | 1 | 2017 |
| Spanish Breast Cancer Research Group | Academic/Hospital | 1 | 0 | 1 | 2022 |
| University of Navarra | Academic/Hospital | 1 | 0 | 1 | 2022 |
| University of Texas at Houston | Academic/Hospital | 1 | 1 | 1 | 2025 |
7 organizations
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