← Mechanisms of action
ITGAL
SINGLE PROTEINHomo sapiens
Preferred name: Leukocyte adhesion glycoprotein LFA-1 alpha ChEMBL ↗
Linked proteins
Drugs acting on this target (8)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| 7hp349 | Activator | experimental | Small molecule | ITGAL activator |
| birt 2584 xx | Inhibitor | experimental | Small molecule | ITGAL inhibitor |
| bms-985521 | Inhibitor | experimental | mAb | ITGAL inhibitor |
| bms587101 | Inhibitor | experimental | Small molecule | ITGAL inhibitor |
| efalizumab (Raptiva) | Inhibitor | withdrawn | mAb | ITGAL inhibitor |
| odulimomab | Inhibitor | experimental | mAb | ITGAL inhibitor |
| rovelizumab (LeukArrest) | Inhibitor | experimental | mAb | ITGAL inhibitor |
| vvn001 | Inhibitor | experimental | Small molecule | ITGAL inhibitor |