← Mechanisms of action
KCNH2
SINGLE PROTEINHomo sapiens
Preferred name: HERG ChEMBL ↗
Linked proteins
Drugs acting on this target (9)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| amiodarone (cordarone) | Blocker | approved | Small molecule | KCNH2 blocker |
| azd-1305 | Blocker | experimental | Small molecule | KCNH2 blocker |
| azd7009 | Blocker | experimental | Small molecule | KCNH2 blocker |
| dofetilide (tikosyn) | Blocker | approved | Small molecule | KCNH2 blocker |
| ibutilide (corvert) | Blocker | approved | Small molecule | KCNH2 blocker |
| sotalol (betapace) | Blocker | approved | Small molecule | KCNH2 blocker |
| vernakalant | Blocker | experimental | Small molecule | HERG blocker |
| azimilide | Inhibitor | experimental | Small molecule | KCNH2 inhibitor |
| tarloxotinib | Inhibitor | experimental | Small molecule | KCNH2 inhibitor |