← Mechanisms of action

S1PR1

SINGLE PROTEINHomo sapiens
Preferred name: Sphingosine 1-phosphate receptor Edg-1 ChEMBL ↗

Linked proteins

Drugs acting on this target (23)

Active Pharmaceutical Ingredient Mechanism Type Approval Status API Type Mechanism of Action
apd-334AgonistexperimentalSmall moleculeS1PR1 agonist
asp4058AgonistexperimentalSmall moleculeS1PR1 agonist
ethoximodAgonistexperimentalSmall moleculeS1PR1 agonist
etrasimod (Velsipity)AgonistapprovedSmall moleculeS1PR1 agonist
krp-203AgonistexperimentalSmall moleculeS1PR1 agonist
mocravimodAgonistexperimentalSmall moleculeSphingosine 1-phosphate receptor Edg-1 agonist
pf-04629991AgonistexperimentalSmall moleculeS1PR1 agonist
ponesimod (Ponvory)AgonistapprovedSmall moleculeS1PR1 agonist
proximodAgonistexperimentalSmall moleculeS1PR1 agonist
sar247799AgonistexperimentalSmall moleculeS1PR1 agonist
scd-044AgonistexperimentalSmall moleculeS1PR1 agonist
siponimod (Mayzent)AgonistapprovedSmall moleculeS1PR1 agonist
cenerimodInhibitorexperimentalSmall moleculeS1PR1 inhibitor
gsk2018682InhibitorexperimentalSmall moleculeS1PR1 inhibitor
bms-986104ModulatorexperimentalSmall moleculeS1PR1 modulator
cenerimodModulatorexperimentalSmall moleculeSphingosine 1-phosphate receptor Edg-1 modulator
etrasimod (Velsipity)ModulatorapprovedSmall moleculeSphingosine 1-phosphate receptor Edg-1 modulator
lc51-0255ModulatorexperimentalSmall moleculeS1PR1 modulator
LC51-0255ModulatorexperimentalSmall moleculeS1PR1 modulator
mocravimodModulatorexperimentalSmall moleculeS1PR1 modulator
opl-002ModulatorexperimentalSmall moleculeS1PR1 modulator
ozanimod (Zeposia)ModulatorapprovedSmall moleculeSphingosine 1-phosphate receptor Edg-1 modulator
vtx002ModulatorexperimentalSmall moleculeS1PR1 modulator