← Mechanisms of action
HBB
SINGLE PROTEINHomo sapiens
Preferred name: Hemoglobin beta chain ChEMBL ↗
Linked proteins
Drugs acting on this target (12)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| lentiglobin bb305 (Zynteglo) | Agonist | approved | Gene therapy | HBB agonist |
| lentiglobin bb305 (Zynteglo) | Exogenous gene | approved | Gene therapy | Hemoglobin beta chain exogenous gene |
| lovotibeglogene autotemcel (Lyfgenia) | Exogenous gene | approved | Gene therapy | Hemoglobin beta chain exogenous gene |
| als20 | Supplementation | experimental | Gene therapy | HBB supplementation |
| autologous cd34+ cells transduced with tns9.3.55 | Supplementation | experimental | Cell therapy | HBB supplementation |
| crispr_scd001 | Supplementation | experimental | Gene therapy | HBB supplementation |
| EDIT-301 | Supplementation | experimental | Gene therapy | HBB supplementation |
| hemoglobin pegylated | Supplementation | experimental | Recombinant protein | HBB supplementation |
| hemoglobin raffimer | Supplementation | experimental | Recombinant protein | HBB supplementation |
| lovotibeglogene autotemcel (Lyfgenia) | Supplementation | approved | Gene therapy | HBB supplementation |
| pegylated carboxyhemoglobin | Supplementation | experimental | Recombinant protein | HBB supplementation |
| tn-1 | Supplementation | experimental | Recombinant protein | HBB supplementation |