← Mechanisms of action
PTPN11
SINGLE PROTEINHomo sapiens
Preferred name: Protein-tyrosine phosphatase 2C ChEMBL ↗
Linked proteins
Drugs acting on this target (16)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| eras-601 | Allosteric antagonist | experimental | Small molecule | PTPN11 allosteric antagonist |
| jab-3312 | Allosteric antagonist | experimental | Small molecule | PTPN11 allosteric antagonist |
| bbp-398 | Antagonist | experimental | Small molecule | SHP2 |
| bpi-442096 | Antagonist | experimental | Small molecule | SHP2 |
| et0038 | Antagonist | experimental | Small molecule | SHP2 |
| gh21 | Antagonist | experimental | Small molecule | SHP2 |
| hs-10381 | Antagonist | experimental | Small molecule | SHP2 |
| icp-189 | Antagonist | experimental | Small molecule | SHP2 |
| gdc-1971 | Inhibitor | experimental | Small molecule | PTPN11 inhibitor |
| hbi-2376 | Inhibitor | experimental | Small molecule | PTPN11 inhibitor |
| iacs-15509 | Inhibitor | experimental | Small molecule | PTPN11 inhibitor |
| jab-3068 | Inhibitor | experimental | Small molecule | PTPN11 inhibitor |
| pf-07284892 | Inhibitor | experimental | Small molecule | PTPN11 inhibitor |
| rly-1971 | Inhibitor | experimental | Small molecule | PTPN11 inhibitor |
| sar442720 | Inhibitor | experimental | Small molecule | PTPN11 inhibitor |
| sh3809 | Inhibitor | experimental | Small molecule | PTPN11 inhibitor |