bbp-398
Small moleculeexperimental
Clinical trial activity
4 trials · 6 clinical orgs · 0 marketing orgs
Phase 1
4
Phase 2
0
Phase 3
0
Phase 4
0
Earliest trial started May 31, 2022 (NCT05375084)
Timeline
2020s
- Jan 1, 2022
Earliest Phase 1 Sponsor(trial)
Indications
Mechanism of action
Chemistry & pharmacology
Loading structure…
SMILES
Cc1c(N2CCC3(CC2)CO[C@@H](C)[C@H]3N)nc(C)n(-c2cccc(Cl)c2Cl)c1=O- Mol. weight
- 437.37 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL5761940 ↗
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06032936 | Phase 1 | Jul 27, 2023 | LianBio LLC, Sun Yat-Sen University |
| NCT05621525 | Phase 1 | Oct 18, 2022 | LianBio LLC, Sichuan University |
| NCT05480865 | Phase 1 | Jul 6, 2022 | Amgen, Navire Pharma Inc. |
| NCT05375084 | Phase 1 | May 31, 2022 | Bristol-Myers Squibb, Navire Pharma Inc. |
Showing 4 of 4 trials
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Organizations
Research & Development (6)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| LianBio LLC | For profit | 2 | 2 | 1 | 2022 |
| Navire Pharma Inc. | For profit | 2 | 2 | 1 | 2022 |
| Amgen | For profit | 1 | 0 | 1 | 2022 |
| Bristol-Myers Squibb | For profit | 1 | 0 | 1 | 2022 |
| Sichuan University | Academic/Hospital | 1 | 0 | 1 | 2022 |
| Sun Yat-Sen University | Academic/Hospital | 1 | 0 | 1 | 2023 |
6 organizations
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