← Mechanisms of action
APP
SINGLE PROTEINRattus norvegicus
Preferred name: Amyloid beta A4 protein ChEMBL ↗
Linked proteins
Drugs acting on this target (30)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| abbv-916 | Antagonist | experimental | mAb | APP antagonist |
| 124i-at-01 | Binding agent | experimental | Peptide | APP binding agent |
| azd2995 | Binding agent | experimental | Small molecule | APP binding agent |
| florbetaben F-18 (neuraceq) | Binding agent | approved | Small molecule | APP binding agent |
| florbetapir (Amyvid) | Binding agent | approved | Small molecule | APP binding agent |
| flutemetamol F-18 (vizamyl) | Binding agent | approved | Small molecule | APP binding agent |
| i-123-mni-168 | Binding agent | experimental | Small molecule | APP binding agent |
| mes-impy | Binding agent | experimental | Small molecule | APP binding agent |
| mk-3328 | Binding agent | experimental | Small molecule | APP binding agent |
| abvac40 | Immunity, active | experimental | Vaccine | APP immunity, active |
| aci-7104.056 | Immunity, active | experimental | Vaccine | APP immunity, active |
| affitope ad01 | Immunity, active | experimental | Vaccine | APP immunity, active |
| affitope ad02 | Immunity, active | experimental | Vaccine | APP immunity, active |
| affitope ad03 | Immunity, active | experimental | Vaccine | APP immunity, active |
| affitope ad04 | Immunity, active | experimental | Vaccine | APP immunity, active |
| alz-101 | Immunity, active | experimental | Vaccine | APP immunity, active |
| lu af20513 | Immunity, active | experimental | Vaccine | APP immunity, active |
| ad-104-a | Inhibitor | experimental | Peptide | APP inhibitor |
| aftobetin | Inhibitor | experimental | Small molecule | APP inhibitor |
| azd2184 | Inhibitor | experimental | Small molecule | APP inhibitor |
| bi 1034020 | Inhibitor | experimental | mAb | APP inhibitor |
| ct1812 | Inhibitor | experimental | Small molecule | APP inhibitor |
| gl101 | Inhibitor | experimental | Small molecule | APP inhibitor |
| khk6640 | Inhibitor | experimental | Small molecule | APP inhibitor |
| mrz-99030 | Inhibitor | experimental | Small molecule | APP inhibitor |
| pf-06751979 | Inhibitor | experimental | Small molecule | APP inhibitor |
| pmn310 | Inhibitor | experimental | mAb | APP inhibitor |
| sodium oligo-mannurarate | Inhibitor | experimental | Small molecule | APP inhibitor |
| azd4694 | Radiopharmaceutical | experimental | Small molecule | APP radiopharmaceutical |
| w372 | Radiopharmaceutical | experimental | Small molecule | APP radiopharmaceutical |