sodium oligo-mannurarate
Small moleculeexperimental
Clinical trial activity
10 trials · 4 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
3
Phase 3
2
Phase 4
4
Earliest trial started Oct 1, 2011 (NCT01453569)
Timeline
Indications
Approved for
Mechanism of action
- Amyloid beta A4 proteinINHIBITOR
APP inhibitor
- Unspecified targetOTHER
Unknown
Various mechanisms proposed inc. inhibition of amyloid beta aggregation and modulation of the gut microbiota. However, the full mechanism is disputed/unknown (PMID: 32632254).
Chemistry & pharmacology
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL4650397 ↗
Also known as
- gv-971
- sodium oligo-mannurarate
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05908695 | Phase 4 | Aug 31, 2023 | Shanghai Greenvalley Pharmaceutical Co., Ltd. |
| NCT05545605 | N/A | Nov 20, 2022 | Southern Medical University |
| NCT05430867 | Phase 4 | Jul 1, 2022 | Jiao Tong University |
| NCT05181475 | Phase 4 | Dec 7, 2021 | Shanghai Greenvalley Pharmaceutical Co., Ltd. |
| NCT05058040 | Phase 4 | Jun 2, 2021 | Shanghai Greenvalley Pharmaceutical Co., Ltd. |
| NCT04520412 | Phase 3 | Oct 27, 2020 | Shanghai Greenvalley Pharmaceutical Co., Ltd. |
| NCT03715114 | Phase 1 | Oct 15, 2018 | Shanghai Greenvalley Pharmaceutical Co., Ltd., Shanghai Xuhui District Central Hospital |
| NCT02986529 | Phase 1 | Nov 1, 2016 | Shanghai Greenvalley Pharmaceutical Co., Ltd. |
| NCT02293915 | Phase 3 | Apr 1, 2014 | Shanghai Greenvalley Pharmaceutical Co., Ltd. |
| NCT01453569 | Phase 2 | Oct 1, 2011 | Jiao Tong University, Shanghai Greenvalley Pharmaceutical Co., Ltd. |
Showing 10 of 10 trials
Page 1 / 1
Organizations
Research & Development (4)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Shanghai Greenvalley Pharmaceutical Co., Ltd. | For profit | 8 | 8 | 4 | 2011 |
| Jiao Tong University | Academic/Hospital | 2 | 1 | 2 | 2011 |
| Shanghai Xuhui District Central Hospital | Academic/Hospital | 1 | 0 | 1 | 2018 |
| Southern Medical University | Academic/Hospital | 1 | 1 | 1 | 2022 |
4 organizations
Page 1 / 1