← Mechanisms of action
Proto-oncogene tyrosine-protein kinase receptor Ret /Nuclear receptor coactivator 4 fusion protein
CHIMERIC PROTEINHomo sapiens
Linked proteins
Drugs acting on this target (2)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| pralsetinib (Gavreto) | Antagonist | approved | Small molecule | Proto-oncogene tyrosine-protein kinase receptor Ret /Nuclear receptor coactivator 4 fusion protein antagonist |
| Selpercatinib (Retevmo) | Antagonist | approved | Small molecule | Proto-oncogene tyrosine-protein kinase receptor Ret /Nuclear receptor coactivator 4 fusion protein antagonist |