← Mechanisms of action
F12
SINGLE PROTEINHomo sapiens
Preferred name: Coagulation factor XII ChEMBL ↗
Linked proteins
Drugs acting on this target (6)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| bismuth subgallate | Activator | experimental | Small molecule | F12 activator |
| aln-f1202 | Antisense inhibitor | experimental | Nucleic acid | F12 antisense inhibitor |
| C1 Esterase Inhibitor (Human) (Cinryze) | Inhibitor | approved | Recombinant protein | Coagulation factor XII inhibitor |
| garadacimab | Inhibitor | approved | mAb | F12 inhibitor |
| ion547 | Inhibitor | experimental | Nucleic acid | F12 inhibitor |
| regn9533 | Inhibitor | experimental | mAb | F12 inhibitor |