CDEK
← Mechanisms of action

F11

SINGLE PROTEINHomo sapiens
Preferred name: Coagulation factor XI ChEMBL ↗

Linked proteins

Drugs acting on this target (26)

Active Pharmaceutical Ingredient Mechanism Type ▲ Approval Status API Type Mechanism of Action
isis 416858AgonistexperimentalNucleic acidF11 agonist
regn7508AntagonistexperimentalmAbF11 antagonist
regn9933AntagonistexperimentalmAbF11 antagonist
adx-626Antisense inhibitorexperimentalNucleic acidF11 antisense inhibitor
city-fxiAntisense inhibitorexperimentalNucleic acidF11 antisense inhibitor
fxi-galnac-sirnaAntisense inhibitorexperimentalNucleic acidF11 antisense inhibitor
srsd107Antisense inhibitorexperimentalNucleic acidF11 antisense inhibitor
AbelacimabInhibitorexperimentalmAbCoagulation factor XI inhibitor
bay1213790InhibitorexperimentalmAbF11 inhibitor
bay2433334InhibitorexperimentalSmall moleculeF11 inhibitor
bms-962212InhibitorexperimentalSmall moleculeF11 inhibitor
bms-986209InhibitorexperimentalSmall moleculeF11 inhibitor
C1 Esterase Inhibitor (Human) (Cinryze)InhibitorapprovedRecombinant proteinCoagulation factor XI inhibitor
ep-7041InhibitorexperimentalRecombinant proteinF11 inhibitor
hrs-4029InhibitorexperimentalSmall moleculeF11 inhibitor
hsk36273InhibitorexperimentalSmall moleculeF11 inhibitor
kn060InhibitorexperimentalSmall moleculeF11 inhibitor
MilvexianInhibitorexperimentalSmall moleculeF11 inhibitor
mk-2060InhibitorexperimentalmAbF11 inhibitor
ono-7684InhibitorexperimentalSmall moleculeF11 inhibitor
shr-2004InhibitorexperimentalmAbF11 inhibitor
shr2285InhibitorexperimentalSmall moleculeF11 inhibitor
xh-s002InhibitorexperimentalSmall moleculeF11 inhibitor
xisomab 3g3InhibitorexperimentalmAbF11 inhibitor
bay2976217SupplementationexperimentalRecombinant proteinF11 supplementation
FrunexianSupplementationexperimentalSmall moleculeF11 supplementation