← Mechanisms of action
GRM5
SINGLE PROTEINHomo sapiens
Preferred name: Metabotropic glutamate receptor 5 ChEMBL ↗
Linked proteins
Drugs acting on this target (15)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| d-aspartate | Activator | experimental | Small molecule | GRM5 activator |
| dasolampanel etibutil | Antagonist | experimental | Small molecule | GRM5 antagonist |
| fenobam | Antagonist | experimental | Small molecule | GRM5 antagonist |
| mavoglurant | Antagonist | experimental | Small molecule | GRM5 antagonist |
| az12713580 | Inhibitor | experimental | Small molecule | GRM5 inhibitor |
| adx10059 | Modulator | experimental | Small molecule | GRM5 modulator |
| azd-2066 | Modulator | experimental | Small molecule | GRM5 modulator |
| basimglurant | Modulator | experimental | Small molecule | GRM5 modulator |
| dipraglurant | Modulator | experimental | Small molecule | GRM5 modulator |
| get 73 | Modulator | experimental | Small molecule | GRM5 modulator |
| ro5011232 | Modulator | experimental | Small molecule | GRM5 modulator |
| ro6806127 | Modulator | experimental | Small molecule | GRM5 modulator |
| azd-2516 | Negative allosteric modulator | experimental | Small molecule | GRM5 negative allosteric modulator |
| stx107 | Negative allosteric modulator | experimental | Small molecule | GRM5 negative allosteric modulator |
| abp688 | Radiopharmaceutical | experimental | Small molecule | GRM5 radiopharmaceutical |