← Mechanisms of action
JAK1
SINGLE PROTEINRattus norvegicus
Preferred name: Jak1 protein ChEMBL ↗
Linked proteins
Drugs acting on this target (30)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| abrocitinib (Cibinqo) | Antagonist | approved | Small molecule | JAK1 antagonist |
| arq-252 | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| ati-1777 | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| azd0449 | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| azd4205 | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| azd4604 | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| cee321 | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| cj-15314 | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| elsubrutinib | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| fzj-003 | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| glpg3121 | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| golidocitinib | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| Ifidancitinib | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| jacketinib | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| kl130008 | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| leo 142397 | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| Lorpucitinib | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| max-40070 | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| pf06263276 | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| qy201 | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| qy211 | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| td-0903 | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| td-3504 | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| td-8236 | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| tdm-180935 | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| tll018 | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| tofacitinib (xeljanz) | Inhibitor | approved | Small molecule | JAK1 inhibitor |
| tq05105 | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| vc005 | Inhibitor | experimental | Small molecule | JAK1 inhibitor |
| vvn461 | Inhibitor | experimental | Small molecule | JAK1 inhibitor |