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Immune Reconstitution Inflammatory Syndrome

Exuberant inflammatory response towards a previously acquired or undiagnosed opportunistic infection. It is frequently seen in AIDS patients following antiretroviral treatment.

Drugs by status

Phase 4 trials (2)

  • methylprednisolone
  • prednisone

Phase 3 trials (3)

  • urea
  • naproxen
  • atorvastatin

Phase 2 trials (1)

  • valganciclovir

Other trials (1)

  • maraviroc

Organizations

Organization Involved with Phase 4 Indications (6)

  • Elan Pharmaceuticals
  • Biogen
  • GlaxoSmithKline
  • Duke University
  • Kilimanjaro Christian Medical College, Tanzania
  • Kibong'oto National Tuberculosis Hospital, Sanya Juu, Tanzania

Organization Involved with Phase 3 Indications (10)

  • Pfizer
  • University of London
  • Cornell University
  • Institute of Tropical Medicine, Belgium
  • Mahidol University
  • University of Cape Town
  • University of Minnesota
  • European and Developing Countries Clinical Trials Partnership (EDCTP)
  • Department of Science and Technology, South Africa
  • Minnesota Medical Foundation

Organization Involved with Phase 2 Indications (2)

  • Instituto Nacional de Enfermedades Respiratorias
  • National Institute of Cancerología

Organization Involved with Other Experimental Indications (8)

  • National Institutes of Health (NIH)
  • National Institute of Allergy and Infectious Diseases (NIAID)
  • University of Pennsylvania
  • Case Western Reserve University
  • Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
  • The Wistar Institute
  • University of the Witwatersrand
  • Instituto Nacional de la Nutrición Salvador Zubiran

CDEK

The Clinical Drug Experience Knowledgebase — tracking drugs, sponsoring organizations, and clinical trials from first-in-human testing through approval.

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