Pick Disease of the Brain
A rare form of DEMENTIA that is sometimes familial. Clinical features include APHASIA; APRAXIA; CONFUSION; ANOMIA; memory loss; and personality deterioration. This pattern is consistent with the pathologic findings of circumscribed atrophy of the poles of the FRONTAL LOBE and TEMPORAL LOBE. Neuronal loss is maximal in the HIPPOCAMPUS, entorhinal cortex, and AMYGDALA. Some ballooned cortical neurons contain argentophylic (Pick) bodies. (From Brain Pathol 1998 Apr;8(2):339-54; Adams et al., Principles of Neurology, 6th ed, pp1057-9)
Drugs by status
Organizations
Organization Involved with Phase 4 Indications (8)
Organization Involved with Phase 3 Indications (7)
Organization Involved with Phase 2 Indications (28)
- Avid Radiopharmaceuticals
- Cyclotherapeutics
- FORUM Pharmaceuticals Inc
- National Institutes of Health (NIH)
- National Human Genome Research Institute (NHGRI)
- National Institute of Neurological Disorders and Stroke (NINDS)
- Chang Gung University
- Cornell University
- Duke University
- HealthPartners Institute
- University of Florida
- University of Louisville
- Columbia University
- Jiao Tong University
- Salford Royal Foundation NHS Trust
- University of Oxford
- CHU Purpan
- University of Nantes
- University of Paris
- Washington University in St. Louis
- University of Western Ontario
- Canadian Institutes of Health Research (CIHR)
- Berry Consultants
- Johnson and Johnson
- University of Rennes
- The Weston A. Price Foundation
- IntraBio Inc
- Prevail Therapeutics
Organization Involved with Phase 1 Indications (14)
- Genzyme
- Axon Neuroscience SE
- Molecular NeuroImaging
- National Eye Institute (NEI)
- Institute for Neurodegenerative Disorders
- Korea Health Industry Development Institute
- New York Medical College
- Northwestern University
- University of Ulm
- University of Ulsan
- University of Utah
- The Marcus Foundation
- BioClinica, Inc.
- Consortium of Canadian Centres for Clinical Cognitive Research
Organization Involved with Other Experimental Indications (2)