Liver Failure, Acute
A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
Subtype terms (2)
More specific conditions that are subtypes of Liver Failure, Acute in the MeSH hierarchy.
- Acute-On-Chronic Liver Failure
111 drugs (59 approved, 52 experimental)
- Massive Hepatic Necrosis
Drugs by status
Phase 4 trials (3)
Phase 3 trials (1)
Phase 2 trials (13)
- hepatocarcinoma-intestine-pancreas protein, human
- diphenhydramine
- lymphocyte immune globulin, anti-thymocyte globulin (equine)
- emricasan
- ornithine aspartate
- measles, mumps, rubella, varicella vaccine
- ornithine
- prednisolone
- sodium chloride
- exosomes from mesenchymal stem cells
- Hepatocyte Growth Factor
- f573
- hmb002
Phase 1 trials (2)
Organizations
Organization Involved with Phase 4 Indications (5)
Organization Involved with Phase 3 Indications (4)
Organization Involved with Phase 2 Indications (10)
Organization Involved with Phase 1 Indications (2)
Organization Involved with Other Experimental Indications (3)