Hereditary Sensory and Motor Neuropathy
A group of slowly progressive inherited disorders affecting motor and sensory peripheral nerves. Subtypes include HMSNs I-VII. HMSN I and II both refer to CHARCOT-MARIE-TOOTH DISEASE. HMSN III refers to hypertrophic neuropathy of infancy. HMSN IV refers to REFSUM DISEASE. HMSN V refers to a condition marked by a hereditary motor and sensory neuropathy associated with spastic paraplegia (see SPASTIC PARAPLEGIA, HEREDITARY). HMSN VI refers to HMSN associated with an inherited optic atrophy (OPTIC ATROPHIES, HEREDITARY), and HMSN VII refers to HMSN associated with retinitis pigmentosa. (From Adams et al., Principles of Neurology, 6th ed, p1343)
Subtype terms (5)
More specific conditions that are subtypes of Hereditary Sensory and Motor Neuropathy in the MeSH hierarchy.
- Alstrom Syndrome
2 drugs (1 approved, 1 experimental)
- Charcot-Marie-Tooth Disease
22 drugs (10 approved, 12 experimental)
- Giant Axonal Neuropathy
1 drug experimental
- Refsum Disease
- Spastic Paraplegia, Hereditary
8 drugs (5 approved, 3 experimental)
Drugs by status
Approved for this indication (1)
Phase 3 trials (1)
Phase 2 trials (1)
Other trials (1)
Organizations
Organization Involved with Phase 4 Indications (2)
Organization Involved with Phase 3 Indications (17)
- INC Research
- Ortho Biotech, Inc.
- Pharnext SA
- Muscular Dystrophy Association
- Katholieke Universiteit Leuven
- University of Manchester
- University of Toronto
- University of Alberta
- Wayne State University
- St. Louis University
- University of Munster
- Seton Hall University
- University of Amsterdam
- Salford Royal Foundation NHS Trust
- Aix-University of Marseille
- Synteract, Inc.
- Charcot-Marie-Tooth Association
Organization Involved with Phase 2 Indications (10)
Organization Involved with Other Experimental Indications (1)