pvsripo
Vaccineexperimental
Clinical trial activity
9 trials · 7 clinical orgs · 0 marketing orgs
Phase 1
6
Phase 2
4
Phase 3
0
Phase 4
0
Earliest trial started Jul 1, 2017 (NCT03043391)
Timeline
Indications
Studied for
- Astrocytoma · Phase 1
- Brain Neoplasms · Phase 2
- Breast Neoplasms · Early Phase 1
- Ependymoma · Phase 1
- Glioblastoma · Phase 2
- Glioma · Phase 1/Phase 2
- Gliosarcoma · Phase 1
- Head and Neck Neoplasms · Phase 1/Phase 2
- Medulloblastoma · Phase 1
- Melanoma · Phase 2
- Neoplasms · Phase 1/Phase 2
- Oligodendroglioma · Phase 1
- Urinary Bladder Neoplasms · Phase 1/Phase 2
Mechanism of action
- Tumor antigensImmunity, active
immunity, active - tumor antigens
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- pvsripo
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04690699 | Phase 1/Phase 2 (Phase 2) | Aug 1, 2021 | Istari Oncology, Inc. |
| NCT04577807 | Phase 2 | Nov 17, 2020 | Istari Oncology, Inc. |
| NCT04479241 | Phase 2 | Oct 21, 2020 | Istari Oncology, Inc. |
| NCT04125719 | Phase 1 | Dec 1, 2019 | Bristol-Myers Squibb, Duke University, Istari Oncology, Inc. |
| NCT03973879 | Phase 1/Phase 2 (Phase 2) | Aug 1, 2019 | Duke University, Genentech, Istari Oncology, Inc. |
| NCT03712358 | Phase 1 | Nov 26, 2018 | Duke University, Istari Oncology, Inc. |
| NCT03564782 | Early Phase 1 (Phase 1) | Sep 24, 2018 | Department of Defense, Duke University, Istari Oncology, Inc. |
| NCT03043391 | Phase 1 | Jul 1, 2017 | Duke University, Musella Foundation, The Andrew McDonough B+ Foundation |
| NCT04599647 | N/A | — | Istari Oncology, Inc. |
Showing 9 of 9 trials
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Organizations
Research & Development (7)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Istari Oncology, Inc. | For profit | 8 | 6 | 3 | 2018 |
| Duke University | Academic/Hospital | 5 | 3 | 2 | 2017 |
| Bristol-Myers Squibb | For profit | 1 | 0 | 1 | 2019 |
| Department of Defense | Government | 1 | 0 | 1 | 2018 |
| Genentech | For profit | 1 | 0 | 1 | 2019 |
| Musella Foundation | Academic/Hospital | 1 | 0 | 1 | 2017 |
| The Andrew McDonough B+ Foundation | Academic/Hospital | 1 | 0 | 1 | 2017 |
7 organizations
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