neoantigen reactive t cells
Cell therapyexperimental
Clinical trial activity
7 trials · 6 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
4
Phase 3
0
Phase 4
0
Earliest trial started Aug 31, 2013 (NCT01967706)
Timeline
Indications
Studied for
- Breast Neoplasms · Phase 2
- Carcinoma, Hepatocellular · Phase 1/Phase 2
- Carcinoma, Non-Small-Cell Lung · Phase 2
- Hematologic Neoplasms · Phase 1
- Intestinal Neoplasms · Phase 2
- Leukemia, Myeloid, Acute · Phase 1
- Multiple Myeloma · Phase 2
- Myelodysplastic Syndromes · Phase 1
- Neoplasms · Phase 2
- Neuroendocrine Tumors · Phase 2
- Ovarian Neoplasms · Phase 2
- Precursor Cell Lymphoblastic Leukemia-Lymphoma · Phase 1
- Rectal Neoplasms · Phase 2
Mechanism of action
- Tumor antigensImmunity, passive
immunity, passive - tumor antigens
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- neoantigen reactive t cells
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06904066 | Phase 1 | Dec 2, 2025 | National Cancer Institute (NCI) |
| NCT04536922 | Phase 2 | Jan 27, 2021 | National Cancer Institute (NCI) |
| NCT03412877 | Phase 2 | Sep 6, 2018 | National Cancer Institute (NCI) |
| NCT03199807 | Phase 1/Phase 2 (Phase 2) | Jul 20, 2017 | Nanjing University |
| NCT03171220 | Phase 1/Phase 2 (Phase 2) | Jun 1, 2017 | Nanjing Medical University, Nanjing University |
| NCT01967706 | N/A | Aug 31, 2013 | Ageo Medical Clinic, Philip Morris |
| NCT04194190 | N/A | — | National Institutes of Health (NIH) |
Showing 7 of 7 trials
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Organizations
Research & Development (6)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| National Cancer Institute (NCI) | Government | 3 | 3 | 2 | 2018 |
| Nanjing University | Academic/Hospital | 2 | 2 | 1 | 2017 |
| Ageo Medical Clinic | Academic/Hospital | 1 | 0 | 1 | 2013 |
| Nanjing Medical University | Academic/Hospital | 1 | 0 | 1 | 2017 |
| National Institutes of Health (NIH) | Government | 1 | 1 | 1 | — |
| Philip Morris | For profit | 1 | 1 | 1 | 2013 |
6 organizations
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