kremezin
Small moleculeexperimental
Clinical trial activity
22 trials · 32 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
10
Phase 3
4
Phase 4
9
Earliest trial started Apr 1, 2004 (NCT00456859)
Timeline
Indications
Approved for
Studied for
- Acute Kidney Injury · Phase 4
- Drugs, Investigational · Phase 4
- Gastroesophageal Reflux · Phase 2
- Healthy Volunteers · Phase 1
- Hepatic Encephalopathy · Phase 2
- Inflammatory Bowel Diseases · Phase 3
- Intestinal Fistula · Phase 3
- Irritable Bowel Syndrome · Phase 2
- Kidney Failure, Chronic · Phase 4
- Pouchitis · Phase 2
- Renal Insufficiency, Chronic · Phase 4
- Solute Carrier Proteins · Phase 4
Mechanism of action
- UnclearUnclear
Unclear unclear
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- ast 120
- ast-120
- ast-120
- kremezin
- kremezin
- renamezin
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07182422 | Phase 4 | Sep 15, 2025 | Chang Gung University, ConMed Corporation |
| NCT04639674 | N/A | Jul 2, 2020 | Chang Gung University, ConMed Corporation, Government of Taiwan, Kaohsiung Medical University, Taichung Veterans General Hospital, Taipei Buddhist Tzu Chi Medical Foundation, Tung's Taiching MetroHarbor Hospital, Tzu Chi University |
| NCT03788252 | Phase 4 | Nov 23, 2018 | Cha Medical University |
| NCT02693613 | Phase 1 | Feb 1, 2016 | Astellas, FibroGen |
| NCT02687841 | Phase 3 | Jan 1, 2016 | Chang Gung University, China Medical University, National Taiwan University, Taipei Medical University, Taoyuan General Hospital |
| NCT02681991 | Phase 4 | Jan 1, 2016 | Daewon Pharmaceutical Co., Ltd., Yonsei University |
| NCT02681952 | Phase 4 | Dec 1, 2015 | Daewon Pharmaceutical Co., Ltd., Yonsei University |
| NCT01458652 | Phase 4 | Jan 1, 2011 | Lim Paik Seong, Tung's Taiching MetroHarbor Hospital |
| NCT01157260 | Phase 4 | Sep 1, 2010 | Ewha Womans University |
| NCT00867698 | Phase 2 | Mar 1, 2009 | Ocera Therapeutics |
| NCT00860431 | Phase 4 | Mar 1, 2009 | CJ HealthCare Corp., Kureha Corporation, Seoul National University |
| NCT01681303 | Phase 4 | Jan 1, 2009 | Chang Gung University |
| NCT00719758 | Phase 1 | Jun 1, 2008 | Astellas, Toray Industries, Inc |
| NCT00587275 | Phase 2 | Oct 1, 2007 | Department of Veteran Affairs, Ocera Therapeutics |
| NCT00558038 | Phase 2 | Sep 1, 2007 | Ocera Therapeutics, Scripps |
| NCT00583128 | Phase 2 | Aug 1, 2007 | Katholieke Universiteit Leuven, Ocera Therapeutics |
| NCT00500682 | Phase 3 | Jul 1, 2007 | Kureha Corporation, Mitsubishi Tanabe |
| NCT00501046 | Phase 3 | Jul 1, 2007 | Kureha Corporation, Mitsubishi Tanabe |
| NCT00583531 | Phase 2 | Mar 1, 2007 | Mayo Clinic, Ocera Therapeutics |
| NCT00583076 | Phase 2 | Feb 1, 2007 | Ocera Therapeutics, University of Rochester |
Showing 20 of 22 trials
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Organizations
Research & Development (32)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Ocera Therapeutics | For profit | 7 | 7 | 2 | 2006 |
| Chang Gung University | Academic/Hospital | 4 | 2 | 3 | 2009 |
| Kureha Corporation | For profit | 3 | 0 | 2 | 2007 |
| Astellas | For profit | 2 | 2 | 1 | 2008 |
| ConMed Corporation | For profit | 2 | 1 | 2 | 2020 |
| Daewon Pharmaceutical Co., Ltd. | For profit | 2 | 2 | 1 | 2015 |
| Mitsubishi Tanabe | For profit | 2 | 2 | 1 | 2007 |
| Tung's Taiching MetroHarbor Hospital | Academic/Hospital | 2 | 1 | 2 | 2011 |
| Yonsei University | Academic/Hospital | 2 | 0 | 1 | 2015 |
| Cha Medical University | Academic/Hospital | 1 | 1 | 1 | 2018 |
| China Medical University | Academic/Hospital | 1 | 0 | 1 | 2016 |
| CJ HealthCare Corp. | For profit | 1 | 0 | 1 | 2009 |
| Department of Veteran Affairs | Government | 1 | 0 | 1 | 2007 |
| Ewha Womans University | Academic/Hospital | 1 | 1 | 1 | 2010 |
| FibroGen | For profit | 1 | 0 | 1 | 2016 |
| Government of Taiwan | Government | 1 | 0 | 1 | 2020 |
| Institute for Health Outcomes and Process Evaluation Reseach | Academic/Hospital | 1 | 1 | 1 | 2004 |
| Jichi Medical University | Academic/Hospital | 1 | 0 | 1 | 2004 |
| Kaohsiung Medical University | Academic/Hospital | 1 | 0 | 1 | 2020 |
| Katholieke Universiteit Leuven | Academic/Hospital | 1 | 0 | 1 | 2007 |
32 organizations
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